USC-OGP 2-DE database Two-dimensional polyacrylamide gel electrophoresis database

USC-OGP 2-DE database  Search by                Maps             Select Remote Interfaces [All Interfaces] SWISS-2DPAGE World-2DPAGE Portal World-2DPAGE Repository Exclude local DBs has only effect if a remote interface is selected

Searching in 'USC-OGP 2-DE database' for entry matching: ARPC5_HUMAN USC-OGP 2-DE database:  ARPC5_HUMAN ARPC5_HUMAN General information about the entry View entry in simple text format Entry name ARPC5_HUMAN Primary accession number O15511 integrated into USC-OGP 2-DE database on  January 17, 2017 (release 1) 2D Annotations were last modified on January 17, 2017 (version 1) General Annotations were last modified on  April 5, 2017 (version 2) Name and origin of the protein Description RecName: Full=Actin-related protein 2/3 complex subunit 5; AltName: Full=Arp2/3 complex 16 kDa subunit; Short=p16-ARC;. Gene name Name=ARPC5 Synonyms=ARC16 Annotated species Homo sapiens (Human) [TaxID: 9606] Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. References [1]   2D GEL CHARACTERIZATION Author 1., Author 2. Submitted (Mar-2011) to Current 2D PAGE maps for identified proteins How to interpret a protein PLATELET_4-7 {PLATELET 4-7} Homo sapiens (Human)   map experimental info   PLATELET_4-7 MAP LOCATIONS: SPOT OGP-0577: pI=5.23; Mw=18044 SPOT OGP-0582: pI=5.40; Mw=17844 PLATELET_5-6 {PLATELET 5-6} Homo sapiens (Human)   map experimental info   PLATELET_5-6 MAP LOCATIONS: SPOT OGP-0851: pI=5.21; Mw=16121 SPOT OGP-0856: pI=5.41; Mw=13405 UVEAL_MELANOMA_3-10 {UVEAL MELANOMA 3-10} Homo sapiens (Human)   map experimental info   UVEAL_MELANOMA_3-10 MAP LOCATIONS: SPOT OGP-1324: pI=5.53; Mw=18450 Cross-references UniProtKB/Swiss-Prot O15511; ARPC5_HUMAN. 2D PAGE maps for identified proteins How to interpret a protein map You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw. Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly. Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed. External data extracted from UniProtKB/Swiss-Prot Extracted from UniProtKB/Swiss-Prot, release: 0.0 Entry name ARPC5_HUMAN Primary accession number O15511 Secondary accession number(s) A6NEC4 Q6PG42 Sequence was last modified on  January 23, 2007 (version 3) Annotations were last modified on  March 15, 2017 (version 145) Name and origin of the protein Description RecName: Full=Actin-related protein 2/3 complex subunit 5; AltName: Full=Arp2/3 complex 16 kDa subunit; Short=p16-ARC; Gene name Name=ARPC5 Synonyms=ARC16 Encoded on Name=ARPC5; Synonyms=ARC16 Keywords Acetylation; Actin-binding; Alternative splicing; Cell projection; Complete proteome; Cytoplasm; Cytoskeleton; Direct protein sequencing; Reference proteome; Ubl conjugation. Copyright Copyrighted by the UniProt Consortium, see http://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License Cross-references EMBL AF006088; AAB64193.1; -; mRNA EMBL AF017807; AAB70561.1; -; mRNA EMBL AL137800; CAC19687.1; -; Genomic_DNA EMBL AL137800; CAI19482.1; -; Genomic_DNA EMBL CH471067; EAW91163.1; -; Genomic_DNA EMBL BC057237; AAH57237.1; -; mRNA CCDS CCDS1357.1; -. [O15511-1]; . CCDS CCDS58050.1; -. [O15511-2]; . RefSeq NP_001257368.1; NM_001270439.1. [O15511-2]; . RefSeq NP_005708.1; NM_005717.3. [O15511-1]; . UniGene Hs.518609; -; . ProteinModelPortal O15511; -; . BioGrid 115399; 57; . DIP DIP-33144N; -; . IntAct O15511; 21; . MINT MINT-2999073; -; . STRING 9606.ENSP00000352918; -; . DrugBank DB08235; N-[2-(2-methyl-1H-indol-3-yl)ethyl]thiophene-2-carboxamide; . iPTMnet O15511; -; . PhosphoSitePlus O15511; -; . BioMuta ARPC5; -; . OGP O15511; -; . SWISS-2DPAGE O15511; -; . EPD O15511; -; . MaxQB O15511; -; . PaxDb O15511; -; . PeptideAtlas O15511; -; . PRIDE O15511; -; . TopDownProteomics O15511-1; -. [O15511-1]; . TopDownProteomics O15511-2; -. [O15511-2]; . DNASU 10092; -; . Ensembl ENST00000294742; ENSP00000294742; ENSG00000162704. [O15511-2]; . Ensembl ENST00000359856; ENSP00000352918; ENSG00000162704. [O15511-1]; . GeneID 10092; -; . KEGG hsa:10092; -; . UCSC uc021pgb.3; human. [O15511-1]; . CTD 10092; -; . DisGeNET 10092; -; . GeneCards ARPC5; -; . HGNC HGNC:708; ARPC5; . HPA HPA022013; -; . HPA HPA031972; -; . MIM 604227; gene; . neXtProt NX_O15511; -; . OpenTargets ENSG00000162704; -; . PharmGKB PA25003; -; . eggNOG KOG3380; Eukaryota; . eggNOG ENOG4111FGV; LUCA; . GeneTree ENSGT00390000014806; -; . HOGENOM HOG000197215; -; . HOVERGEN HBG050583; -; . InParanoid O15511; -; . KO K05754; -; . OMA ADNATCQ; -; . OrthoDB EOG091G0R2J; -; . PhylomeDB O15511; -; . TreeFam TF319716; -; . Reactome R-HSA-2029482; Regulation of actin dynamics for phagocytic cup formation; . Reactome R-HSA-3928662; EPHB-mediated forward signaling; . Reactome R-HSA-5663213; RHO GTPases Activate WASPs and WAVEs; . Reactome R-HSA-6798695; Neutrophil degranulation; . Reactome R-HSA-8856828; Clathrin-mediated endocytosis; . SIGNOR O15511; -; . ChiTaRS ARPC5; human; . GeneWiki ARPC5; -; . GenomeRNAi 10092; -; . PRO PR:O15511; -; . Proteomes UP000005640; Chromosome 1; . Bgee ENSG00000162704; -; . CleanEx HS_ARPC5; -; . ExpressionAtlas O15511; baseline and differential; . Genevisible O15511; HS; . GO GO:0015629; C:actin cytoskeleton; TAS:ProtInc; . GO GO:0005885; C:Arp2/3 protein complex; IDA:FlyBase; . GO GO:0005737; C:cytoplasm; TAS:ProtInc; . GO GO:0005829; C:cytosol; TAS:Reactome; . GO GO:0005768; C:endosome; IEA:Ensembl; . GO GO:0070062; C:extracellular exosome; IDA:UniProtKB; . GO GO:0005576; C:extracellular region; TAS:Reactome; . GO GO:1904813; C:ficolin-1-rich granule lumen; TAS:Reactome; . GO GO:0005925; C:focal adhesion; IDA:UniProtKB; . GO GO:0030426; C:growth cone; IEA:Ensembl; . GO GO:0034774; C:secretory granule lumen; TAS:Reactome; . GO GO:0005200; F:structural constituent of cytoskeleton; IDA:FlyBase; . GO GO:0030036; P:actin cytoskeleton organization; TAS:ProtInc; . GO GO:0051639; P:actin filament network formation; IEA:Ensembl; . GO GO:0034314; P:Arp2/3 complex-mediated actin nucleation; IDA:FlyBase; . GO GO:0016477; P:cell migration; IMP:CACAO; . GO GO:0048013; P:ephrin receptor signaling pathway; TAS:Reactome; . GO GO:0038096; P:Fc-gamma receptor signaling pathway involved in phagocytosis; TAS:Reactome; . GO GO:0097581; P:lamellipodium organization; IEA:Ensembl; . GO GO:0030011; P:maintenance of cell polarity; IEA:Ensembl; . GO GO:0061024; P:membrane organization; TAS:Reactome; . GO GO:0031023; P:microtubule organizing center organization; IEA:Ensembl; . GO GO:0006928; P:movement of cell or subcellular component; TAS:ProtInc; . GO GO:0043312; P:neutrophil degranulation; TAS:Reactome; . GO GO:0021769; P:orbitofrontal cortex development; IEA:Ensembl; . GO GO:0014909; P:smooth muscle cell migration; IEA:Ensembl; . Gene3D 1.25.40.190; -; 1; . InterPro IPR006789; ARPC5; . PANTHER PTHR12644; PTHR12644; 1; . Pfam PF04699; P16-Arc; 1; . PIRSF PIRSF039096; p16-ARC; 1; . SUPFAM SSF69103; SSF69103; 1; .

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